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Home Insulin, Medicines, & Other Diabetes Treatments

Uses, side effects, dosage, cost, and more

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October 25, 2021
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Zegalogue can cause mild or serious side effects. The following lists contain some of the key side effects that may occur with Zegalogue. These lists do not include all possible side effects.

For more information about the possible side effects of Zegalogue, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or bothersome.

Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with Zegalogue, you can do so through MedWatch.

Mild side effects

Mild side effects* of Zegalogue can include:

Most of these side effects may go away within a few hours to a couple of days. But if they become more severe or don’t go away, talk with your doctor or pharmacist.

* This is a partial list of mild side effects from Zegalogue. To learn about other mild side effects, talk with your doctor or pharmacist, or see Zegalogue’s prescribing information.
† For more information about this side effect, see “Side effect details” below.

Serious side effects

Serious side effects from Zegalogue aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or the local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

Serious side effects of Zegalogue can include:

* For more information about this side effect, see “Side effect details” below.

Side effects in children

Zegalogue is approved for use in children ages 6 years and older.

In clinical studies, side effects of Zegalogue reported in children were similar to those reported in adults who took the drug. These are described above and below. But diarrhea wasn’t reported in children in these studies.

Zegalogue side effects, especially nausea and vomiting, were more common in children ages 12 to 17 years than in younger children or in adults.

Side effect details

Here’s some detail on certain side effects this drug may cause.

Nausea and vomiting

Nausea and vomiting may occur after receiving Zegalogue. In clinical studies, these side effects were very common, especially in children ages 12 to 17 years.

It’s important to note that nausea and vomiting can also be symptoms of hypoglycemia. And it’s possible for your blood sugar to drop again after you’ve received Zegalogue.

After you’ve been given a dose of Zegalogue, your caregiver should move you onto your side. This is to help prevent you from choking if you vomit.

If you have nausea and vomiting after you’ve recovered, check your blood sugar to make sure it’s not too low again. If you have nausea and vomiting that’s severe or doesn’t go away, talk with your doctor right away. These side effects can increase your risk of another episode of hypoglycemia.

Headache

Headache is possible after receiving Zegalogue. This side effect was common in clinical studies of the drug.

It’s important to note that headache can also be a symptom of high or low blood sugar.

If you have a headache after receiving Zegalogue, check your blood sugar to make sure it’s in the right range.

If your blood sugar is in the correct range for you, but you still have a headache that’s bothersome, talk with your doctor or pharmacist. They can recommend a suitable pain reliever.

Allergic reaction

As with most drugs, some people can have an allergic reaction after receiving Zegalogue. It’s not known how often this side effect occurred with the medication in clinical studies.

Symptoms of a mild allergic reaction can include:

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:

  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your tongue, mouth, or throat
  • trouble breathing

Call your doctor right away if you have an allergic reaction to Zegalogue, as the reaction could become severe. Call 911 or the local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

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